Rapid Derivatization of Phenolic and Oxime Hydroxyl with Isonicotinoyl Chloride under Aqueous Conditions and Its Application in LC-MS/MS Profiling Multiclass Steroids.
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DOI: 10.1021/acs.analchem.2c04151
Abstract: Quantification of steroids possesses a crucial clinical value in early diagnosis and prognosis evaluation of various endocrine diseases. However, it is still challenging to realize feasible analysis of estrogens, androgens, progestogens, and corticoids within one… read more here.
Keywords: isonicotinoyl chloride; multiclass steroids; aqueous conditions; derivatization ... See more keywords