Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation.
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DOI: 10.1021/acs.bioconjchem.1c00099
Abstract: Antibody-drug conjugates (ADCs) have demonstrated great therapeutic potential due to their ability to target the delivery of potent cytotoxins. However, the heterogeneous nature of conventional drug conjugation strategies can affect the safety, efficacy, and stability… read more here.
Keywords: igg; ligation; labeling native; efficient labeling ... See more keywords