Articles with "isopetasin desensitizes" as a keyword



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The anti‐migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel

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Published in 2017 at "British Journal of Pharmacology"

DOI: 10.1111/bph.13917

Abstract: The mechanism of the anti‐migraine action of extracts of butterbur [Petasites hybridus (L.) Gaertn.] is unknown. Here, we investigated the ability of isopetasin, a major constituent of these extracts, to specifically target TRPA1 channel and… read more here.

Keywords: isopetasin desensitizes; butterbur extracts; extracts isopetasin; anti migraine ... See more keywords