Preventive effect of apigenin against isoproterenol‐induced apoptosis in cardiomyoblasts
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22213
Abstract: We investigated the effect of apigenin, a dietary flavonoid, on isoproterenol hydrochloride (ISO)‐induced apoptotic signaling in cardiomyoblast H9C2 cells. The results showed that apigenin treatment (10 µM) prevented ISO (31.25 μM)‐induced lipid peroxidative levels and antioxidants status… read more here.
Keywords: effect apigenin; h9c2 cells; isoproterenol; effect ... See more keywords
Beneficial effect of sodium thiosulfate extends beyond myocardial tissue in isoproterenol model of infarction: Implication for nootropic effects
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22606
Abstract: One of the common negative impacts in the management of acute myocardial infarction is cognitive decline. Using the rat model of isoproterenol (ISO)‐induced myocardial infarction, we assessed the cardioprotective effect of sodium thiosulfate (STS) and… read more here.
Keywords: isoproterenol; infarction; model; effect sodium ... See more keywords
The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173524
Abstract: Myocardial infarction (MI) eventually exacerbates inflammatory response due to the release of inflammatory and pro-inflammatory factors. The aim of this study is to explore the protective efficacy of piperine supplementation against the inflammatory response in… read more here.
Keywords: isoproterenol; iso; group; inflammation ... See more keywords
Cardioprotective effects of a Fructus Aurantii polysaccharide in isoproterenol-induced myocardial ischemic rats.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.11.063
Abstract: CALB-3, a purified acidic hetero-polysaccharide isolated from Fructus aurantii, has been shown to exert cardioprotective effects in vitro. Recently, we investigated the protective effects of CALB-3 on myocardial injury and its possible mechanisms of action… read more here.
Keywords: isoproterenol; cardioprotective effects; fructus aurantii; effects fructus ... See more keywords
Cardioprotective properties of natural medicine in isoproterenol induced myocardial damage in the male Albino rats
Sign Up to like & getrecommendations! Published in 2021 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2021.04.012
Abstract: The main aim of this study is to investigate cardioprotective properties of natural medicine inmyocardial damage induced male Albino rats. The aqueous extractof Allium sativumwas used for the determination of phenolic compounds and flavonoids. The… read more here.
Keywords: medicine; isoproterenol; cardioprotective properties; albino rats ... See more keywords
Unmasking the borderline coarctation: the utility of isoproterenol in the paediatric cardiac catheterisation laboratory
Sign Up to like & getrecommendations! Published in 2018 at "Cardiology in the Young"
DOI: 10.1017/s1047951118000239
Abstract: Abstract Background One indication for intervention in coarctation of the aorta is a peak-to-peak gradient >20 mmHg. Gradients may be masked in patients under general anaesthesia and may be higher during exercise. Isoproterenol was given… read more here.
Keywords: intervention; cardiac catheterisation; isoproterenol; coarctation ... See more keywords
P3509Leukocyte derived tumour necrosis factor modulates cardiac function in health and disease
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0373
Abstract: Tumour necrosis factor alpha (TNFα) regulates both normal and pathophysiological cardiac function. The regulatory role of TNFα derived from different sources (leukocyte versus cardiac cells) in cardiac physiology is unclear. Deficiency of iRhom2 protein prevents… read more here.
Keywords: isoproterenol; cardiac function; irhom2 deficient; mice ... See more keywords
Cardiac macrophages regulate isoproterenol-induced Takotsubo-like cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.156236
Abstract: Takotsubo syndrome (TTS) is an acute, stress-induced cardiomyopathy that occurs predominantly in women after extreme physical and/or emotional stress. To date, our understanding of the molecular basis for TTS remains unknown and, consequently, specific therapies… read more here.
Keywords: cardiac macrophages; macrophages regulate; like cardiomyopathy; isoproterenol ... See more keywords
Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model
Sign Up to like & getrecommendations! Published in 2021 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-021-02112-4
Abstract: Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD . We… read more here.
Keywords: dmd; isoproterenol; nicorandil isoproterenol; isoproterenol induced ... See more keywords
The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenol-induced Cardiotoxicity
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DOI: 10.2174/1381612825666190619145025
Abstract: Background: Isoproterenol (ISO) is a non-selective β-adrenergic agonist. Our aims were to investigate the autophagy and cell death pathways including apoptosis and necrosis in ISO-induced car-diac injury in a dose-dependent manner. Methods: Male Sprague-Dawley rats… read more here.
Keywords: iso iso; isoproterenol; iso; dose dependent ... See more keywords
Icariin ameliorates oxidative stress-induced inflammation, apoptosis, and heart failure in isoproterenol-challenged Wistar rats
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2023.66481.14589
Abstract: Objective(s): Cardiovascular diseases are widespread across the globe, and heart failure (HF) accounts for the majority of heart-associated deaths. Target-based drug therapy is much needed for the management of heart failure. We have designed this… read more here.
Keywords: heart failure; oxidative stress; heart; isoproterenol ... See more keywords