Benzo[de]isoquinoline-1,3-dione condensed asymmetric azaacenes as strong acceptors
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DOI: 10.1039/d2ra01074g
Abstract: We have designed and synthesized three novel benzo[de]isoquinoline-1,3-dione (BQD) condensed asymmetric azaacenes, BQD-TZ, BQD-AP and BQD-PA, with different end groups of 1,2,5-thiadiazole, acenaphthylene and phenanthrene. The triisopropylsilylethynyl groups were grafted to increase the solubility and… read more here.
Keywords: isoquinoline dione; condensed asymmetric; bqd bqd; asymmetric azaacenes ... See more keywords
Isoquinoline-1,3-dione-derived conjugated polymers for field-effect transistors: Synthesis, properties, and the effect of inner aromatic bridges
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DOI: 10.1039/d3py00063j
Abstract: Isoquinoline-1,3-dione (IQD) is a novel electron-withdrawing building block. However, its polymer derivatives have been rarely constructed and studied. Herein, we report a series of polymers (P1−P3) based on three novel... read more here.
Keywords: isoquinoline dione; dione derived; effect; conjugated polymers ... See more keywords
Design, synthesis, and biological evaluation of a novel series of 2-(2,6-dioxopiperidin-3-yl)isoquinoline-1,3(2H,4H)-dione derivatives as cereblon modulators
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2022.2087219
Abstract: Abstract In the current study, we designed and synthesised a novel series of 2-(2,6-dioxopiperidin-3-yl)isoquinoline-1,3(2H,4H)-dione derivatives as cereblon (CRBN) modulators. The results of the CCK8 assay revealed potent antiproliferative activity for the selected compound 10a against… read more here.
Keywords: novel series; isoquinoline dione; series dioxopiperidin; compound 10a ... See more keywords