Synthesis and SAR studies of novel isoquinoline and tetrahydroisoquinoline derivatives as melatonin receptor ligands.
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DOI: 10.1002/cmdc.202100658
Abstract: In our constant search for new successors of Agomelatine, we report herein another new series of compounds resulting from bio-isosteric modulation of the naphthalene ring. New isoquinoline and tetrahydroisoquinoline derivatives were synthesized and pharmacologically evaluated.… read more here.
Keywords: sar studies; studies novel; synthesis sar; tetrahydroisoquinoline derivatives ... See more keywords