Synthesis of Pyrrolo[2,3-c]isoquinolines via the Cycloaddition of Benzyne with Arylideneaminopyrroles: Photophysical and Crystallographic Study
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DOI: 10.1021/acsomega.9b02043
Abstract: An efficient and quick access toward a series of (E)-2-arylideneaminopyrroles 6 and to their benzyne-promoted aza-Diels–Alder cycloaddition products is provided. These products are three pyrrolo[2,3-c]isoquinolines 8a–c substituted in position 5 with different electron-acceptor (A) or… read more here.
Keywords: cycloaddition; synthesis pyrrolo; study; isoquinolines via ... See more keywords
Uncanonical Semireduction of Quinolines and Isoquinolines via Regioselective HAT-Promoted Hydrosilylation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c11664
Abstract: Heterocycles are the backbone of modern medical chemistry and drug development. The derivatization of "an olefin" inside aromatic rings represents an ideal approach to access functionalized saturated heterocycles from abundant aromatic building blocks. Here, we… read more here.
Keywords: isoquinolines via; regioselective hat; via regioselective; semireduction quinolines ... See more keywords
Tuneable access to isoquinolines via a transition-metal-free C(sp3)–C(sp3) bond cleavage rearrangement reaction
Sign Up to like & getrecommendations! Published in 2019 at "Organic Chemistry Frontiers"
DOI: 10.1039/c9qo00427k
Abstract: A novel divergent synthesis of multi-substituted isoquinolines via C(sp3)–C(sp3) bond cleavage rearrangement reactions was realized. read more here.
Keywords: sp3 bond; sp3 sp3; bond cleavage; sp3 ... See more keywords
Catalytic Synthesis of Isoquinolines via Intramolecular Migration of N-Aryl Sulfonyl Groups on 1,5-Yne-Imines
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of the Chemical Society of Japan"
DOI: 10.1246/bcsj.20190301
Abstract: Isoquinolines are ubiquitous structural motifs in a variety of bioactive compounds, including medicinal agents and natural products. The development of novel strategies for the preparation of isoqu... read more here.
Keywords: synthesis isoquinolines; via intramolecular; intramolecular migration; migration aryl ... See more keywords