Applications of Isosteres of Piperazine in the Design of Biologically Active Compounds: Part 1.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00726
Abstract: Piperazine and homopiperazine are well-studied heterocycles in drug design that have found gainful application as scaffolds and terminal elements and for enhancing the aqueous solubility of a molecule. The optimization of drug candidates that incorporate… read more here.
Keywords: design; isosteres piperazine; applications isosteres; piperazine design ... See more keywords
Applications of Isosteres of Piperazine in the Design of Biologically Active Compounds: Part 2.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00729
Abstract: Applications of piperazine and homopiperazine in drug design are well-established, and these heterocycles have found use as both scaffolding and terminal elements and also as a means of introducing a water-solubilizing element into a molecule.… read more here.
Keywords: design; isosteres piperazine; applications isosteres; piperazine design ... See more keywords