Systematic interpolation method predicts protein chromatographic elution with salt gradients, pH gradients and combined salt/pH gradients.
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DOI: 10.1002/biot.201600636
Abstract: A methodology is presented to predict protein elution behavior from an ion exchange column using both individual or combined pH and salt gradients based on high-throughput batch isotherm data. The buffer compositions are first optimized… read more here.
Keywords: elution; salt gradients; interpolation method; isotherm data ... See more keywords