Investigating Protein Binding with the Isothermal Ligand‐induced Resolubilization Assay
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DOI: 10.1002/cbic.202300773
Abstract: Target engagement assays typically detect and quantify the direct physical interaction of a protein of interest and its ligand through stability changes upon ligand binding. Commonly used target engagement methods detect ligand‐induced stability by subjecting… read more here.
Keywords: ligand induced; ligand; protein; isothermal ligand ... See more keywords