Synthesis of Thiazoles and Isothiazoles via Three-Component Reaction of Enaminoesters, Sulfur, and Bromodifluoroacetamides/Esters.
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DOI: 10.1021/acs.orglett.0c01275
Abstract: A three-component strategy for the synthesis of thiazoles and isothiazoles has been developed by employing enaminoesters, fluorodibromoiamides/ester, and sulfur. The thiazoles and isothiazoles were formed via two C-F bond cleavages along with the formation of… read more here.
Keywords: synthesis thiazoles; thiazoles isothiazoles; via three; isothiazoles via ... See more keywords