Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts
Sign Up to like & getrecommendations! Published in 2021 at "Chembiochem"
DOI: 10.1002/cbic.202100089
Abstract: Sinapigladioside is a rare isothiocyanate‐bearing natural product from beetle‐associated bacteria (Burkholderia gladioli) that might protect beetle offspring against entomopathogenic fungi. The biosynthetic origin of sinapigladioside has been elusive, and little is known about bacterial isothiocyanate… read more here.
Keywords: biosynthesis sinapigladioside; isothiocyanate; biosynthesis; sinapigladioside antifungal ... See more keywords
Anti-rheumatic activity of Phenethyl isothiocyanate via inhibition of histone deacetylase-1.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109095
Abstract: Rheumatoid Arthritis (RA) affects approximately 1% of the total world population. Despite incessant research and development of new therapeutic agents, management of RA is still a troublesome affair. Histone Deacetylase 1 (HDAC1) is an epigenetic… read more here.
Keywords: phenethyl isothiocyanate; isothiocyanate; activity phenethyl; histone deacetylase ... See more keywords
Synthesis and characterization of two novel red-shifted isothiocyanate BODIPYs and their application in protein conjugation
Sign Up to like & getrecommendations! Published in 2020 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2020.108646
Abstract: Abstract Fluorescent organic small molecules are very important tools for researchers in the fields of biochemistry and biotechnology, and boron-dipyrromethene (BODIPY) class of organic fluorophores gained much attention in recent years due to their remarkable… read more here.
Keywords: isothiocyanate; application; characterization two; conjugation ... See more keywords
Multitactic Preplant Soil Fumigation with Allyl Isothiocyanate in Cut Flowers and Strawberry
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DOI: 10.21273/horttech04362-19
Abstract: Allyl isothiocyanate (AITC) is a glucosinolate produced in cruciferous plant species. AITC is known to act as a pesticide on microorganisms, insects, and weeds. Synthetic AITC is registered as a biopesticide for agricultural soil treatment… read more here.
Keywords: control efficacy; soil; allyl isothiocyanate; isothiocyanate ... See more keywords
Allyl-, Butyl- and Phenylethyl-Isothiocyanate Modulate Akt–mTOR and Cyclin–CDK Signaling in Gemcitabine- and Cisplatin-Resistant Bladder Cancer Cell Lines
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231910996
Abstract: Combined cisplatin–gemcitabine treatment causes rapid resistance development in patients with advanced urothelial carcinoma. The present study investigated the potential of the natural isothiocyanates (ITCs) allyl-isothiocyanate (AITC), butyl-isothiocyanate (BITC), and phenylethyl-isothiocyanate (PEITC) to suppress growth and… read more here.
Keywords: cell; isothiocyanate; gemcitabine cisplatin; gemcitabine ... See more keywords
Spiroleiferthione A and Oleiferthione A: Two Unusual Isothiocyanate-Derived Thioketone Alkaloids from Moringa oleifera Lam. Seeds
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DOI: 10.3390/ph16030452
Abstract: Spiroleiferthione A (1), with a 2-thiohydantoin a heterocyclic spiro skeleton, and oleiferthione A (2), an imidazole-2-thione derivative, were isolated from the aqueous extract of Moringa oleifera Lam. seeds. The unprecedented structures of 1 and 2… read more here.
Keywords: lam seeds; spiroleiferthione oleiferthione; moringa oleifera; isothiocyanate ... See more keywords
Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of oncology"
DOI: 10.3892/ijo.2017.4084
Abstract: Benzyl isothiocyanate (BITC), and phenethyl isothiocyanate (PEITC) have been demonstrated to induce anticancer function in many human cancer cells and also inhibit cancer cell migration and invasion. However, there are no studies that show BITC… read more here.
Keywords: isothiocyanate; cell; migration invasion; bitc peitc ... See more keywords