Articles with "isotope coded" as a keyword



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Determination of parabens in domestic sewage by isotope-coded derivatization coupled with high performance liquid chromatography-tandem mass spectrometry

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Published in 2017 at "Microchemical Journal"

DOI: 10.1016/j.microc.2016.10.026

Abstract: Abstract We have established an isotope labeling protocol for determining parabens in wastewater, based on a pair of isotope-coded derivatization reagents, by high performance liquid chromatography (LC) and electrospray mass spectrometry (ESI-MS). The pair of… read more here.

Keywords: isotope; isotope coded; coded derivatization; derivatization ... See more keywords
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Research Progress in Analysis of Small Molecule Metabolites in Bio-matrices by Stable Isotope Coded Derivatization Combining with Liquid Chromatography–tandem Mass Spectrometry

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Published in 2017 at "Chinese Journal of Analytical Chemistry"

DOI: 10.1016/s1872-2040(17)61026-0

Abstract: Abstract Stable isotope coded derivatization (ICD) is an isotope labeling technique for specific functional group of the target analytes through chemical derivatization. ICD combined with liquid chromatography–tandem mass spectrometry (LC-MS/MS) enables systematically analyzing the biomolecules… read more here.

Keywords: bio matrices; isotope; analysis; isotope coded ... See more keywords
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Multiplexed Analysis of Endogenous Guanidino Compounds via Isotope-Coded Doubly Charged Labeling: Application to Lung Cancer Tissues as a Case.

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Published in 2021 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.1c03835

Abstract: Endogenous guanidino compounds (GCs), nitrogen-containing metabolites, have very important physiological activities and participate in biochemical processes. Therefore, accurately characterizing the distribution of endogenous GCs and monitoring their concentration variations are of great significance. In this… read more here.

Keywords: analysis; endogenous guanidino; charged labeling; doubly charged ... See more keywords

Isotope-Coded Maleimide Affinity Tags for Proteomics Applications.

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Published in 2021 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.1c00206

Abstract: Isotope-coded affinity tags (ICATs) are valuable tools for mass spectrometry-based quantitative proteomics, in particular, for comparison of protein (cysteine-residue) thiol oxidation state in normal, stressed, and diseased tissue. However, the iodoacetamido electrophile used in most… read more here.

Keywords: affinity tags; maleimide affinity; isotope coded; coded maleimide ... See more keywords
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Isotope-coded protein label based quantitative proteomic analysis reveals significant up-regulation of apolipoprotein A1 and ovotransferrin in the myopic chick vitreous

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-12650-7

Abstract: This study used isotope-coded protein label (ICPL) quantitative proteomics and bioinformatics analysis to examine changes in vitreous protein content and associated pathways during lens-induced eye growth. First, the vitreous protein profile of normal 7-day old… read more here.

Keywords: protein; coded protein; apolipoprotein ovotransferrin; analysis ... See more keywords