Quantitative Mass Spectrometry by Isotope Dilution and Multiple Reaction Monitoring (MRM).
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6990-6_20
Abstract: Selected reaction monitoring (SRM) is used in molecular profiling to detect and quantify specific known proteins in complex mixtures. Using isotope dilution (Barnidge et al., Anal Chem 75(3):445-451, 2003) methodologies, peptides can be quantified without… read more here.
Keywords: mass; reaction monitoring; reaction; isotope dilution ... See more keywords
Comparative study on quantitation of human myoglobin by both isotope dilution mass spectrometry and surface plasmon resonance based on calibration-free analysis
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02504-z
Abstract: The activity of proteins rather than the concentration of proteins in biopharmaceutical and in vitro diagnostics are often the primary focus. Nonetheless, development of a calibration-free concentration analysis (CFCA) approach that accurately quantifies the concentration… read more here.
Keywords: analysis; human myoglobin; calibration free; concentration ... See more keywords
A Stable Isotope Dilution Assay for Multi-class Antibiotics in Pregnant Urines by LC–MS/MS
Sign Up to like & getrecommendations! Published in 2020 at "Chromatographia"
DOI: 10.1007/s10337-020-03866-3
Abstract: Abstract An accurate assay suitable for human biomonitoring of multiclass antibiotics preferred for veterinary use is currently lacking. In this study, we developed a liquid chromatography-triple quadrupole tandem mass spectrometry (LC–QqQ–MS/MS) method for analysis of… read more here.
Keywords: dilution assay; multi class; class antibiotics; stable isotope ... See more keywords
Preparation and calibration of a 231Pa reference material
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-019-06711-6
Abstract: A 231Pa reference material has been characterized for amount of protactinium. This reference material is primarily intended for calibration of 233Pa tracers produced for 235U–231Pa model age measurements associated with nuclear forensics and nuclear safeguards.… read more here.
Keywords: reference material; reference; 231pa reference; calibration ... See more keywords
Isotope Dilution LC-MS/MS Method for Glycine Betaine in Manila Clam (Tapes philippinarum)
Sign Up to like & getrecommendations! Published in 2019 at "Food Analytical Methods"
DOI: 10.1007/s12161-019-01469-9
Abstract: Glycine betaine (GB) is a natural compound with demonstrated metabolic functions in mammals and beneficial effects on the human body: it protects cells under osmotic stress, as an organic osmolyte, and acts as a methylating… read more here.
Keywords: tapes philippinarum; glycine betaine; method; manila ... See more keywords
Quantification of Cl-PAHs and their parent compounds in fish by improved ASE method and stable isotope dilution GC-MS.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.109775
Abstract: This study aimed at developing a simple and accurate method for determination of emerging chlorinated polycyclic aromatic hydrocarbons (Cl-PAHs) in fish by stable isotope dilution gas chromatography tandem mass spectrometry. Fish samples were extracted by… read more here.
Keywords: method; ase method; stable isotope; improved ase ... See more keywords
Application and validation of isotope dilution method (IDM) for predicting bioavailability of hydrophobic organic contaminants in soil.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.01.108
Abstract: Risk assessment of hydrophobic organic contaminants (HOCs) using the total chemical concentration following exhaustive extraction may overestimate the actual availability of HOCs to non-target organisms. Existing methods for estimating HOC bioavailability in soil have various… read more here.
Keywords: soil; dilution method; isotope dilution; bioavailability ... See more keywords
Simultaneous determination of nine neonicotinoids in human urine using isotope-dilution ultra-performance liquid chromatography-tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.04.144
Abstract: Neonicotinoids (neonics), a class of systemic insecticides, have been frequently detected in pollen, vegetables, and fruits. Recently, an increasing concern has been aroused for human exposure to neonics. However, biological monitoring for quantifying body burden… read more here.
Keywords: dilution ultra; mass spectrometry; liquid chromatography; isotope dilution ... See more keywords
Stable isotope dilution assay (SIDA) and HS-SPME-GCMS quantification of key aroma volatiles for fruit and sap of Australian mango cultivars.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2016.11.130
Abstract: Reported herein is a high throughput method to quantify in a single analysis the key volatiles that contribute to the aroma of commercially significant mango cultivars grown in Australia. The method constitutes stable isotope dilution… read more here.
Keywords: mango cultivars; mango; fruit sap; key aroma ... See more keywords
Isotope dilution determination for the trace level of 4(5)-methylimidazole in beverages using dispersive liquid-liquid microextraction coupled with ESI-HPLC-MS/MS.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.10.145
Abstract: In this study, a rapid and reliable pretreatment method called dispersive liquid-liquid microextraction (DLLME) was developed for the determination of 4(5)-methylimidazole (4-MeI) in beverages. The clean-up samples were analyzed by a high performance liquid chromatography… read more here.
Keywords: liquid; determination; dispersive liquid; liquid liquid ... See more keywords
Accurate analysis of parabens in human urine using isotope-dilution ultrahigh-performance liquid chromatography-high resolution mass spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2017.12.038
Abstract: An analytical method that utilizes isotope-dilution ultrahigh-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS or called UHPLC-HRMS) was developed, and validated to be highly precise and accurate for the detection of nine… read more here.
Keywords: analysis; ultrahigh performance; liquid chromatography; dilution ultrahigh ... See more keywords