A sex-sensitive LC-MS/MS method with isotopic internal standard for prazosin bioequivalence: bridging precision medicine and generic drug policy in China
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DOI: 10.3389/fphar.2025.1592731
Abstract: Objective To develop a rapid, sensitive, and high-throughput liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for prazosin quantification in human plasma, validate its application in bioequivalence studies, and investigate sex-specific pharmacokinetic differences in a Chinese population.… read more here.
Keywords: prazosin; isotopic internal; internal standard; sex ... See more keywords