Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9232-4_5
Abstract: Lysine acetylation is an important posttranslational modification (PTM) that regulates the function of proteins by affecting their localization, stability, binding, and enzymatic activity. Aberrant acetylation patterns have been observed in numerous diseases, most notably cancer,… read more here.
Keywords: labeling quantitative; acetylation; acetylation histones; proteomics acetylation ... See more keywords
Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies.
Sign Up to like & getrecommendations! Published in 2018 at "Protein expression and purification"
DOI: 10.1016/j.pep.2017.12.005
Abstract: N-acylethanolamine acid amidase (NAAA) is an N-terminal nucleophile (Ntn) enzyme with a catalytic cysteine residue that has highest activity at acidic pH. The most prominent substrate hydrolyzed is palmitoylethanolamine (PEA), which regulates inflammation. Inhibitors of… read more here.
Keywords: acid amidase; acylethanolamine acid; isotopic labeling;
Kendrick Mass Defect Variation to Decipher Isotopic Labeling in Brain Metastases Studied by Mass Spectrometry Imaging.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03916
Abstract: Besides many other applications, isotopic labeling is commonly used to decipher the metabolism of living biological systems. By giving a stable isotopically labeled compound as a substrate, the biological system will use this labeled nutrient… read more here.
Keywords: mass; isotopic labeling; decipher; mass spectrometry ... See more keywords
Isotopic Labeling Experiments Solve the Hedycaryol Problem.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04021
Abstract: Hedycaryol is a widespread sesquiterpene alcohol and important biosynthetic intermediate toward eudesmols and guaiols. A full NMR assignment for this compound has been hampered because of the unique molecular mechanics of its conformers in complex… read more here.
Keywords: problem; solve hedycaryol; isotopic labeling; hedycaryol ... See more keywords
Corrigendum: In Vivo Isotopic Labeling of Symbiotic Bacteria Involved in Cellulose Degradation and Nitrogen Recycling within the Gut of the Forest Cockchafer (Melolontha hippocastani)
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.00488
Abstract: [This corrects the article on p. 1970 in vol. 8, PMID: 29075241.]. read more here.
Keywords: labeling symbiotic; vivo isotopic; symbiotic bacteria; isotopic labeling ... See more keywords