(Z)-Trifluoromethyl-Trisubstituted Alkenes or Isoxazolines: Divergent Pathways from the Same Allene.
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DOI: 10.1021/acs.orglett.0c02546
Abstract: Because of a charge-dipole interaction involving nonbonding electron pairs on fluorine, protonation of trifluoromethyl allenes leads to tri- or tetrasubstituted alkenes with high (Z)-selectivity. Treatment of the same allenes with catalytic Au(I) initiates a reaction… read more here.
Keywords: pathways allene; alkenes isoxazolines; trisubstituted alkenes; isoxazolines divergent ... See more keywords