Co-Delivery of Doxorubicin and Survivin shRNA-Expressing Plasmid Via Microenvironment-Responsive Dendritic Mesoporous Silica Nanoparticles for Synergistic Cancer Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Research"
DOI: 10.1007/s11095-017-2264-6
Abstract: PurposeThe present study is aimed at designing an appropriate co-delivery system for chemotherapeutic drugs and gene drugs with high loading capacity, on-demand release behaviors, efficient endosomal escape, and enhanced nucleic localization, thereby providing efficacious antitumor… read more here.
Keywords: isur pdna; delivery; mesoporous silica; cancer ... See more keywords
PEG modified trimethyl chitosan based nanoparticles for the codelivery of doxorubicin and iSur-pDNA
Sign Up to like & getrecommendations! Published in 2019 at "Materials Letters"
DOI: 10.1016/j.matlet.2018.11.161
Abstract: Abstract Doxorubicin (DOX) is one of the commonly used chemotherapeutic agents, but its clinical use is restricted by systemic toxicity and tumor multidrug resistance. To overcome these barriers, PEG modified trimethyl chitosan based nanoparticles (NPs)… read more here.
Keywords: modified trimethyl; pdna; trimethyl chitosan; chitosan based ... See more keywords