Itaconate Has Limited Protective Effects in Experimental Malaria Models
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DOI: 10.1002/eji.202451595
Abstract: In severe malaria, dysregulated metabolism and excessive inflammatory responses contribute to fatal outcomes. Therapeutic strategies that address both metabolic and inflammatory balances are thus required. Itaconate, a metabolite produced by aconitate decarboxylase 1 (ACOD1), is… read more here.
Keywords: limited protective; protective effects; itaconate limited; malaria ... See more keywords