Targeting the itch–scratch vicious circle in atopic eczema
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Dermatology"
DOI: 10.1111/bjd.21027
Abstract: et al . 4 report two long-term studies assessing the efficacy and tolerance of nemolizumab (a humanized IL-31RA monoclonal antibody) in addition to topical anti-inflammatory agents in adolescent and adult patients with AE. The paper… read more here.
Keywords: scratch vicious; vicious circle; atopic eczema; targeting itch ... See more keywords
Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abn4819
Abstract: Itch sensation provokes the scratch reflex to protect us from harmful stimuli in the skin. Although scratching transiently relieves acute itch through activation of mechanoreceptors, it propagates the vicious itch-scratch cycle in chronic itch by… read more here.
Keywords: scratch; skin; scratch cycle; itch ... See more keywords