Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy.
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DOI: 10.1073/pnas.2216230120
Abstract: Gastrin releasing peptide receptor (GRPR), a member of the bombesin (BBN) G protein-coupled receptors, is aberrantly overexpressed in several malignant tumors, including those of the breast, prostate, pancreas, lung, and central nervous system. Additionally, it… read more here.
Keywords: itch therapy; cancer itch; releasing peptide; itch ... See more keywords