Pharmacokinetics and Pharmacodynamics of Itepekimab in Healthy Adults and Patients With Asthma: Phase I First-in-Human and First-in-Patient Trials.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and translational science"
DOI: 10.1111/cts.13157
Abstract: Itepekimab is a monoclonal antibody that targets interleukin-33 and has been shown to reduce airway inflammation and associated tissue damage in preclinical studies. We assessed the safety, tolerability, pharmacokinetics, and pharmacodynamic profiles of single-ascending and… read more here.
Keywords: healthy adults; pharmacokinetics pharmacodynamics; itepekimab; patients asthma ... See more keywords