An iterative strategy to design 4-1BB agonist nanobodies de novo with generative AI models
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DOI: 10.1038/s41598-025-10241-5
Abstract: The 4-1BB receptor, a key member of the tumor necrosis factor receptor (TNFR) family, represents a highly promising target for cancer immunotherapy. In this study, we developed a novel in silico pipeline to design VHH… read more here.
Keywords: design 1bb; 1bb agonist; iterative strategy; agonist nanobodies ... See more keywords