Nonsense‐mediated mRNA decay efficiency influences bleeding severity in ITGA2B c.2659C > T (p.Q887X) knock‐in mice
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DOI: 10.1111/cge.13975
Abstract: Glanzmann's thrombasthenia (GT) is a severe hemorrhagic disease. It is caused by mutations in ITGA2B or ITGB3, which are the respective genes encoding integrin αIIb and β3. Despite widespread mutational analysis, the mechanisms underlying the… read more here.
Keywords: bleeding severity; mice; 2659c q887x; itga2b 2659c ... See more keywords