Integrin β3 regulates apical dendritic morphology of pyramidal neurons throughout hippocampal CA3.
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DOI: 10.1002/hipo.23530
Abstract: In excitatory hippocampal pyramidal neurons, integrin β3 is critical for synaptic maturation and plasticity in vitro. Itgb3 is a potential autism susceptibility gene that regulates dendritic morphology in the cerebral cortex in a cell-specific manner.… read more here.
Keywords: pyramidal neurons; morphology; itgb3; apical dendritic ... See more keywords
Novel homozygous silent mutation of ITGB3 gene caused Glanzmann thrombasthenia
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DOI: 10.3389/fped.2022.1062900
Abstract: Glanzmann thrombasthenia (GT) is a rare inherited disease characterized by mucocutaneous bleeding due to the abnormalities in quantity or quality of platelet membrane GP IIb (CD41) or GP IIIa (CD61). GP IIb and GP IIIa… read more here.
Keywords: homozygous silent; itgb3; glanzmann thrombasthenia; itgb3 gene ... See more keywords