ITGB4 Deficiency in Airway Epithelium Aggravates RSV Infection and Increases HDM Sensitivity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912095
Abstract: Background The heterogeneity of RSV-infected pathology phenotype in early life is strongly associate with increased susceptibility of asthma in later life. However, the inner mechanism of this heterogeneity is still obscure. ITGB4 is a down-regulated… read more here.
Keywords: itgb4 deficiency; rsv infection; infection; hdm sensitivity ... See more keywords
ITGB4 deficiency induces mucus hypersecretion by upregulating MUC5AC in RSV-infected airway epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.66215
Abstract: Respiratory syncytial virus (RSV) infection is the main cause of bronchiolitis in children. Excessive mucus secretion is one of the primary symbols in RSV related lower respiratory tract infections (RSV-related LRTI), which is closely associated… read more here.
Keywords: itgb4 deficiency; mucus hypersecretion; rsv; muc5ac ... See more keywords