Articles with "iti" as a keyword



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cis- and trans-Ligand Effects on the Inverse trans-Influence in [UVI(O)(L)Cl4]0/- (L = Unidentate Ligand) Complexes.

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Published in 2020 at "Inorganic chemistry"

DOI: 10.1021/acs.inorgchem.0c00778

Abstract: A comprehensive exploration of the inverse trans-influence (ITI) phenomenon in a series of cis-[UVI(O)(L)Cl4]0/- and trans-[UVI(O)(L)Cl4]0/- complexes involving a wide variety of neutral and anionic unidentate ligands L, using relativistic density functional theory, threw light… read more here.

Keywords: cl4; inverse trans; chemistry; iti ... See more keywords
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P–421 Down-expression of glycolytic pathway-related protein A1 is associated with the pathogenesis of recurrent pregnancy loss

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Published in 2021 at "Human Reproduction"

DOI: 10.1093/humrep/deab130.420

Abstract: How does glycolytic pathway-related protein A1 (GPRPA1) relate to the pathogenesis of recurrent pregnancy loss (RPL)? GPRPA1 was found as a substrate of ITI-H4 to modulate the inflammatory response and was down-expressed in the sera… read more here.

Keywords: gprpa1; pathogenesis; iti; placental cell ... See more keywords
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The Atlanta Protocol: Immune Tolerance Induction in Pediatric Patients with Hemophilia a and Inhibitors on Emicizumab

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-114249

Abstract: Introduction: The formation of neutralizing anti-factor VIII (fVIII) antibodies, called inhibitors, is a challenging complication in hemophilia A care. While novel non-factor therapies significantly reduce bleeding symptoms in patients with hemophilia A and inhibitors, the… read more here.

Keywords: tolerance; advisory board; board; iti ... See more keywords
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Successful of Immune Tolerance Induction (R-ITI) with Simoctocog Alfa (rhFVIII) in Hemophilia a Patients and High-Titer Inhibitors

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-114615

Abstract: Backgroud: The appearance of inhibitors (INH) is the most serious complication in hemophilia A (HA) patients. The primary objective is their eradication. Usually the primary ITI was performed with the same concentrate causing INH development,… read more here.

Keywords: inhibitor; treatment; alfa; simoctocog alfa ... See more keywords
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Evaluation of Predictors of Outcome in Immune Tolerance Induction Treatment of Hemophilia Α Patients with High-Responding Inhibitors

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Published in 2017 at "Blood"

DOI: 10.1182/blood.v130.suppl_1.2357.2357

Abstract: Introduction: Inhibitor development remains a major complication for patients with hemophilia A. Inhibitors are alloantibodies that neutralize factor (F) VIII activity, which impairs the hemostatic effect of infused FVIII concentrate. Immune tolerance induction (ITI) consists… read more here.

Keywords: inhibitor; response; treatment; success ... See more keywords