A psychiatric disorder risk polymorphism of ITIH3 is associated with multiple neuroimaging phenotypes in young healthy adults
Sign Up to like & getrecommendations! Published in 2022 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13347
Abstract: The inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) gene contains 24 exons and spans 14.2 kb of the genome. A large genome-wide association study (GWAS) suggested that the single-nucleotide polymorphism (SNP) rs2535629 (G/A, risk allele G)… read more here.
Keywords: risk allele; itih3; brain; risk ... See more keywords
Downregulation of ITIH3 contributes to cisplatin-based chemotherapy resistance in ovarian carcinoma via the Bcl-2 mediated anti-apoptosis signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13646
Abstract: Platinum resistance of ovarian cancer is one of the primary factors of poor prognosis and inter-α-trypsin inhibitor heavy chain 3 (ITIH3) is a potential DDP resistance-associated gene. The present study assessed protein expression levels of… read more here.
Keywords: itih3; ovarian cancer; expression; resistance ... See more keywords