ITIM receptors: more than just inhibitors of platelet activation.
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DOI: 10.1182/blood-2016-12-720185
Abstract: Since their discovery, immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptors have been shown to inhibit signaling from immunoreceptor tyrosine-based activation motif (ITAM)-containing receptors in almost all hematopoietic cells, including platelets. However, a growing body of evidence… read more here.
Keywords: itim containing; itim; platelet activation; activation ... See more keywords
LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416136
Abstract: Leukocyte-associated immunoglobulin (Ig)-like receptor 1 (LAIR1, CD305) belongs to the family of immune-inhibitory receptors and is widely expressed on hematopoietic mature cells, particularly on immune cells. Four different types of ligands of LAIR1 have been… read more here.
Keywords: itim containing; containing receptor; hematological neoplasms; receptor involved ... See more keywords