Genetic variants in toll‐like receptor 4 are associated with lack of steroid‐responsiveness in pediatric ITP patients
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Hematology"
DOI: 10.1002/ajh.25716
Abstract: Although the most common front‐line therapies for immune thrombocytopenia (ITP) have been in use for decades, it is still not possible to predict an individual patient's clinical course and response to therapy. Patients are managed… read more here.
Keywords: toll like; response; itp patients; like receptor ... See more keywords
Comparison of 1D a 2D ITP-MS performance parameters and application possibilities: ultratrace determination of B vitamins in human urine.
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DOI: 10.1002/elps.202100209
Abstract: A possibility to investigate analytes at ultra-low concentration levels still remains a hot topic in bioanalysis. In this area various preconcentration techniques are an integral part of analytical procedures. When applying electromigration separation techniques, an… read more here.
Keywords: human urine; itp method; performance parameters; itp ... See more keywords
iTRAQ‐based quantitative proteomics analysis of immune thrombocytopenia patients before and after Qishunbaolier treatment
Sign Up to like & getrecommendations! Published in 2020 at "Rapid Communications in Mass Spectrometry"
DOI: 10.1002/rcm.8993
Abstract: Rationale Treatment of immune thrombocytopenia (ITP) usually involves long‐term use of immunosuppressive corticosteroids and splenectomy. However, these treatments often have side effects in patients. The Mongolian medicine Qishunbaolier (QSBLE) has a high curative effect, reduces… read more here.
Keywords: analysis; treatment; qsble treatment; immune thrombocytopenia ... See more keywords
Recurrence of immune thrombocytopenia at the time of SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04130-2
Abstract: Dear Editor On March 2020, the World Health Organization declared current outbreak of the 2019 coronavirus disease (COVID19), caused by SARS-CoV-2, a global pandemic. Since its recent identification, little is known about managing infected patients,… read more here.
Keywords: recurrence; time; immune thrombocytopenia; sars cov ... See more keywords
Eltrombopag in pediatric chronic and refractory ITP: data from a retrospective multicenter study from Lebanon
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Hematology"
DOI: 10.1007/s00277-022-04804-z
Abstract: About 20% to 30% of pediatric patients with immune thrombocytopenia (ITP) develop chronic or refractory disease lasting 12 months or more that can be challenging to treat. Eltrombopag is being used after failure of previous… read more here.
Keywords: study; chronic refractory; therapy; itp ... See more keywords
Efficacy and safety of eltrombopag in persistent and newly diagnosed ITP in clinical practice
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DOI: 10.1007/s12185-017-2275-4
Abstract: Eltrombopag is safe and effective in primary chronic ITP. However, lack of clinical trials avoids a clear demonstration of its utility in newly diagnosed and persistent ITP. Our aim here is to report Spanish results… read more here.
Keywords: newly diagnosed; diagnosed itp; chronic itp; efficacy ... See more keywords
Acute immune thrombocytopenia following SARS-CoV-2 vaccination in chronic ITP patients and a healthy individual
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hematology"
DOI: 10.1007/s12185-021-03235-2
Abstract: As the vaccination program for COVID-19 progresses worldwide, rare but significant adverse events associated with vaccination are becoming a global concern. In the field of hematology, exacerbation of idiopathic thrombocytopenic purpura (ITP) or acute-onset immune… read more here.
Keywords: hematology; sars cov; immune thrombocytopenia; vaccination ... See more keywords
Autoimmune-mediated thrombocytopenia after allogeneic hematopoietic stem cell transplantation: significance of detecting reticulated platelets and glycoprotein-specific platelet autoantibodies
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DOI: 10.1007/s12185-021-03272-x
Abstract: Autoimmune hematological disorders are rare complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Diagnosis of immune thrombocytopenia (ITP) is challenging, especially after allo-HSCT, because various complications such as graft-versus-host disease, disease relapse, viral infection, thrombotic… read more here.
Keywords: allogeneic hematopoietic; cell transplantation; itp; platelet ... See more keywords
The structure, function, and clinical use of the thrombopoietin receptor agonist avatrombopag.
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DOI: 10.1016/j.blre.2021.100909
Abstract: Thrombopoietin regulates platelet production through activation of the thrombopoietin receptor (TPO-R). TPO-R agonists (TPO-RAs) are available to treat thrombocytopenia in chronic immune thrombocytopenia (ITP), chronic liver disease (CLD) patients who are undergoing a procedure, severe… read more here.
Keywords: thrombopoietin; avatrombopag; tpo; thrombopoietin receptor ... See more keywords
Evaluation of IVIG response in relation to Th1/Th2 cytokines in pediatricm immune thrombocytopenia.
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DOI: 10.1016/j.cyto.2019.05.014
Abstract: Immune thrombocytopenia (ITP) is a common immune-mediated bleeding disorder in children, and intravenous immunoglobulin (IVIG) is widely used as the initial therapy of ITP. Effective predictive factors of response to IVIG in ITP are important… read more here.
Keywords: itp patients; ivig response; immune thrombocytopenia; ivig ... See more keywords
Interleukin-37 reduces inflammation and impairs phagocytosis of platelets in immune thrombocytopenia (ITP).
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DOI: 10.1016/j.cyto.2019.154853
Abstract: Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet count with heterogeneous bleeding manifestations. Severe bleeding in ITP is not completely related with low platelet count. Fcγ receptor (FcγR)-mediated platelet destruction is one… read more here.
Keywords: platelet count; phagocytosis; thrombocytopenia itp; immune thrombocytopenia ... See more keywords