Erythrocyte Inosine triphosphatase activity: A potential biomarker for adverse events during combination antiretroviral therapy for HIV
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DOI: 10.1371/journal.pone.0191069
Abstract: The purine analogues tenofovir and abacavir are precursors of potential substrates for the enzyme Inosine 5’-triphosphate pyrophosphohydrolase (ITPase). Here, we investigated the association of ITPase activity and ITPA genotype with the occurrence of adverse events… read more here.
Keywords: antiretroviral therapy; itpase activity; combination antiretroviral; adverse events ... See more keywords