Sign Up to like & get
recommendations!
0
Published in 2020 at "Environmental Toxicology"
DOI: 10.1002/tox.23031
Abstract: Radiotherapy is a common therapy method for nasopharyngeal carcinoma (NPC) treatment; however, radioresistance greatly limits the clinical efficiency and prognosis of NPC patients. Therefore, it is extremely urgent to reveal the underlying mechanism contributing to…
read more here.
Keywords:
itraconazole;
radioresistance;
npc spheroids;
ferroptosis ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2407-4
Abstract: PurposeThe purpose of this study was to explore the feasibility of developing amorphous solid dispersion (ASD) by inducing acid-base interaction at an elevated temperature using hot melt extrusion.MethodsItraconazole and glutaric acid, which do not form salt…
read more here.
Keywords:
melt extrusion;
solid dispersion;
itraconazole;
amorphous solid ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2018 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2018.01.004
Abstract: INTRODUCTION Invasive fungal infections are an increasing cause of mortality and morbidity in high risk patient populations such as those on immunosuppressive therapy. Triazole antifungals are recommended for the prevention and treatment of such infections.…
read more here.
Keywords:
hydroxy itraconazole;
itraconazole;
lcms;
voriconazole posaconazole ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.04.057
Abstract: Hydroxypropyl-β-cyclodextrin (HP-β-CD) is known to enable absorption of the lipophilic drug itraconazole. Since the interaction between HP-β-CD and itraconazole is characterized by a non-lineair, AP-type phase-solubility diagram, the present study aimed to investigate the influence…
read more here.
Keywords:
dilution;
cyclodextrin;
itraconazole;
water ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14166
Abstract: Oral itraconazole has variable pharmacokinetics and risks of adverse events associated with high plasma exposure. An inhalation formulation of itraconazole (PUR1900) is being developed to treat allergic bronchopulmonary aspergillosis, an allergic inflammatory disease occurring in…
read more here.
Keywords:
phase study;
study pur1900;
itraconazole;
formulation itraconazole ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00134-21
Abstract: Conventional itraconazole (C-ITZ) suffers from absorption variability. SUBA-itraconazole (S-ITZ) is more bioavailable than C-ITZ at steady-state in a fed condition, but there are no data comparing the two under a fasted state. ABSTRACT Conventional itraconazole…
read more here.
Keywords:
itraconazole itz;
single dose;
itraconazole;
conventional itraconazole ... See more keywords
Photo from wikipedia
Sign Up to like & get
recommendations!
0
Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1219-5
Abstract: Tamoxifen is an antiestrogen drug that is widely used in the adjuvant chemotherapy of estrogen receptor-α (ERα)-positive breast cancer. Chemotherapy could suppress immune function in breast cancer patients, which may cause invasive fungal infections (IFIs).…
read more here.
Keywords:
itraconazole tamoxifen;
itraconazole;
tamoxifen;
voriconazole fluconazole ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.634286
Abstract: Candida krusei (C. krusei) has been recently recognized as an important pathogen involved in mycotic mastitis of cows. The phenotypic and molecular characteristics of 15 C. krusei clinical isolates collected from cows with clinical mastitis…
read more here.
Keywords:
mastitis;
itraconazole;
itraconazole resistant;
krusei ... See more keywords