Processability and Oral Bioavailability Improvement of Itraconazole by Particle Engineering Technique
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DOI: 10.1208/s12249-022-02486-4
Abstract: The current study aimed to improve the processability and oral bioavailability of itraconazole (ITZ) via spherical agglomeration. ITZ-spherical agglomerates (ITZ-SA) and ITZ-poloxamer 407-spherical agglomerates (ITZ-PLX-SA) were optimized using Box-Behnken design. Here, the drug release was… read more here.
Keywords: processability oral; oral bioavailability; processability; itz plx ... See more keywords