Evaluation of Ivermectin vs Permethrin for Treating Scabies-Summary of a Cochrane Review.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2019.0279
Abstract: Clinical Question Is the use of ivermectin in patients infested with scabies associated with improved clinical and safety outcomes compared with permethrin? Bottom Line Both ivermectin and permethrin treatment were associated with high clearance rates.… read more here.
Keywords: low certainty; ivermectin permethrin; evaluation ivermectin; certainty evidence ... See more keywords
Suppressing ROS‐TFE3‐dependent autophagy enhances ivermectin‐induced apoptosis in human melanoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27490
Abstract: Melanoma is an aggressive skin malignancy with a high mortality rate; however, successful treatment remains a clinical challenge. Ivermectin, a broad‐spectrum antiparasitic drug, has recently been characterized as a potential anticancer agent due to its… read more here.
Keywords: apoptosis; ivermectin induced; autophagy; ivermectin ... See more keywords
A protocol of trial of ivermectin in COVID‐19 treatment critically changed after its completion
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28505
Abstract: We read the article by Abd-Elsalam et al.1 in Journal of Medical Virology with great interest. The authors conducted a randomized controlled trial to evaluate the efficacy of ivermectin for COVID-19 infected patients. They demonstrated… read more here.
Keywords: virology; trial; ivermectin; ivermectin covid ... See more keywords
Potential of ivermectin as an active ingredient of the attractive toxic sugar baits against the Indian malaria vectors Anopheles culicifacies and Anopheles stephensi.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7217
Abstract: BACKGROUND Attractive toxic sugar bait (ATSB) is a novel vector control tool that exploits the sugar feeding behavior of mosquitoes. The current study aims to evaluate the efficacy of ivermectin based ATSB against insecticide susceptible… read more here.
Keywords: attractive toxic; indian malaria; ivermectin; mortality ... See more keywords
Ivermectin accelerates autophagic death of glioma cells by inhibiting glycolysis through blocking GLUT4 mediated JAK/STAT signaling pathway activation
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Toxicology"
DOI: 10.1002/tox.23440
Abstract: This study aimed to investigate the regulatory effect of ivermectin (IVM) on energy metabolism in glioma progression, and provide a reference for the treatment of glioma. read more here.
Keywords: ivermectin accelerates; death glioma; accelerates autophagic; autophagic death ... See more keywords
Antiviral Drug Ivermectin at Nanomolar Concentrations Inhibits Glycine-Induced Chloride Current in Rat Hippocampal Neurons
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-021-05125-3
Abstract: Ivermectin (IVM) belongs to the class of macrocyclic lactones, which is used as an antiparasitic agent. At present, the researchers focus on possibility to use IVM in treatment of certain forms of cancer and viral… read more here.
Keywords: concentrations inhibits; drug ivermectin; antiviral drug; ivermectin nanomolar ... See more keywords
Synthesis of sodium 5-sulfate-ivermectin and disodium 4″,5-disulfate-ivermectin
Sign Up to like & getrecommendations! Published in 2018 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-018-2146-z
Abstract: Treatment of ivermectin with sulfuric acid–acetic anhydride in pyridine gives sodium 5-sulfate-ivermectin and disodium 4″,5-disulfate-ivermectin. The synthesized salts are water-soluble compounds with promising antiparasitic activity. read more here.
Keywords: disodium disulfate; ivermectin disodium; sulfate ivermectin; sodium sulfate ... See more keywords
Evaluation of Culex quinquefasciatus wings asymmetry after exposure of larvae to sublethal concentration of ivermectin
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-06963-5
Abstract: The surviving insects submitted to chemical control have morphological alterations that impact on their mechanisms of resistance and their final development. Those changes are detected and measured using physical features related to symmetry, specifically named… read more here.
Keywords: culex quinquefasciatus; group; exposure; asymmetry ... See more keywords
Efficacy of ivermectin to control Strongyloides stercoralis infection in sheltered dogs.
Sign Up to like & getrecommendations! Published in 2019 at "Acta tropica"
DOI: 10.1016/j.actatropica.2018.11.014
Abstract: In dogs, information on treatments against S. stercoralis infection is rare and anecdotal. The aim of the present work was to evaluate the treatment outcome of S. stercoralis natural infection in sheltered dogs. Furthermore, based… read more here.
Keywords: stercoralis infection; treatment; infection; infection sheltered ... See more keywords
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2020.104787
Abstract: Abstract Although several clinical trials are now underway to test possible therapies, the worldwide response to the COVID-19 outbreak has been largely limited to monitoring/containment. We report here that Ivermectin, an FDA-approved anti-parasitic previously shown… read more here.
Keywords: ivermectin inhibits; drug ivermectin; approved drug; ivermectin ... See more keywords
Antibiotic ivermectin preferentially targets renal cancer through inducing mitochondrial dysfunction and oxidative damage.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.08.097
Abstract: Renal cell carcinoma (RCC) is the most aggressive type of genitourinary cancer and highly resistant to current available therapies. In this work, we investigated the effects and mechanism of anti-parasitic agent ivermectin in RCC. We… read more here.
Keywords: rcc; rcc cells; mitochondrial dysfunction; ivermectin ... See more keywords