Synthesis and Clinical Examination of Novel Formulations of Ivermectin, Albendazole and Niclosamide for the Treatment of Equine Gastrointestinal Helminthoses
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DOI: 10.18502/ijpa.v18i1.12381
Abstract: Background: This study aimed to develop new complex preparations of ivermectin, niclosamide and albendazole based on solid-phase mechanochemical technology, and to evaluate their efficacy against equine nematodosis and cestodosis. Methods: Novel formulation of antiparasitic paste… read more here.
Keywords: clinical examination; examination novel; ivermectin albendazole; synthesis clinical ... See more keywords
Pharmacokinetic Characterization and Comparative Bioavailability of an Innovative Orodispersible Fixed-Dose Combination of Ivermectin and Albendazole: A Single Dose, Open Label, Sequence Randomized, Crossover Clinical Trial in Healthy Volunteers
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DOI: 10.3389/fphar.2022.914886
Abstract: Soil-transmitted helminths are intestinal worm diseases transmitted through the soil. Available treatments are albendazole and/or ivermectin. The co-administration of existing drugs is an appropriate strategy. A fixed-dose combination adds practical advantages mainly considering mass drug… read more here.
Keywords: combination ivermectin; fixed dose; combination; dose combination ... See more keywords
Safety and Tolerability of Ivermectin and Albendazole Mass Drug Administration in Lymphatic Filariasis Endemic Communities of Tanzania: A Cohort Event Monitoring Study
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DOI: 10.3390/ph15050594
Abstract: Ivermectin and albendazole (IA) combination preventive chemotherapy to all at-risk populations is deployed to eliminate lymphatic filariasis. Although safety monitoring is imperative, data from Sub-Saharan Africa is scarce. We conducted a large-scale active safety surveillance… read more here.
Keywords: mass drug; safety; mda; ivermectin albendazole ... See more keywords