Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities: The I-TECH Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.0189
Abstract: Importance Ivermectin, an inexpensive and widely available antiparasitic drug, is prescribed to treat COVID-19. Evidence-based data to recommend either for or against the use of ivermectin are needed. Objective To determine the efficacy of ivermectin… read more here.
Keywords: disease; trial; ivermectin treatment; randomized clinical ... See more keywords
Gastrointestinal effects of ivermectin treatment in rats infected with Strongyloides venezuelensis.
Sign Up to like & getrecommendations! Published in 2019 at "Acta tropica"
DOI: 10.1016/j.actatropica.2019.03.024
Abstract: We aimed to evaluate the effects of ivermectin treatment on gastrointestinal morphology and function after Strongyloides venezuelensis infection. Male rats composed Control (C), Parasitized (Sv), Ivermectin (IVM) and Parasitized and treated with Ivermectin (Sv/IVM) groups.… read more here.
Keywords: infection; ivermectin treatment; strongyloides venezuelensis; ivm ... See more keywords
Ivermectin treatment in lactating mares results in suboptimal ivermectin exposure in their suckling foals.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2021.109511
Abstract: The management of equine strongyles has become problematic over the last decade because of an increased prevalence of drug-resistant isolates worldwide. Therapeutic options are therefore limited, leaving macrocyclic lactones as the most often effective drug… read more here.
Keywords: treatment lactating; lactating mares; exposure; mares results ... See more keywords
Effect of sainfoin (Onobrychis viciifolia) on cyathostomin eggs excretion, larval development, larval community structure and efficacy of ivermectin treatment in horses
Sign Up to like & getrecommendations! Published in 2022 at "Parasitology"
DOI: 10.1017/s0031182022000853
Abstract: Abstract Abstract Alternative strategies to chemical anthelmintics are needed for the sustainable control of equine strongylids. Bioactive forages like sainfoin (Onobrychis viciifolia) could contribute to reducing drug use, with the first hints of in vitro… read more here.
Keywords: larval; sainfoin; ivermectin treatment; efficacy ... See more keywords
Mouse models of Loa loa
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09442-0
Abstract: Elimination of the helminth disease, river blindness, remains challenging due to ivermectin treatment-associated adverse reactions in loiasis co-infected patients. Here, we address a deficit in preclinical research tools for filarial translational research by developing Loa… read more here.
Keywords: loa loa; loa mouse; loa; ivermectin treatment ... See more keywords
Effectiveness and adverse events of ivermectin treatment for scabies in 30 infant patients: report from a German single centre
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.16554
Abstract: Scabies is a globally prevalent parasitic skin infestation characterized by severe pruritus and a heterogeneous clinical picture depending on the immune status of the individual. Epidemiologic studies reveal a higher susceptibility for young, old and,… read more here.
Keywords: treatment; ivermectin treatment; treatment scabies; adverse events ... See more keywords
Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.625991
Abstract: Objective: The aim of the present study was repositioning of ivermectin in treatment of gastric cancer (GC) by computational prediction based on gene expression profiles of human and mouse model of GC and validations with… read more here.
Keywords: ivermectin; treatment gastric; gastric cancer; ivermectin treatment ... See more keywords
Effectiveness and Safety of a Single-Dose Ivermectin Treatment for Uncomplicated Strongyloidiasis in Immunosuppressed Patients (ImmunoStrong Study): The Study Protocol
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10070812
Abstract: Strongyloidiasis affects an estimated 600 million people worldwide, especially in tropical and subtropical areas. Single-dose ivermectin treatment has shown to be effective among immunocompetent patients with uncomplicated strongyloidiasis. Here, we present the protocol of the… read more here.
Keywords: strongyloidiasis; uncomplicated strongyloidiasis; study; ivermectin treatment ... See more keywords