Articles with "jab1" as a keyword



Identification of a seven-long non-coding RNA signature associated with Jab1/CSN5 in predicting hepatocellular carcinoma

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Published in 2021 at "Cell Death Discovery"

DOI: 10.1038/s41420-021-00560-7

Abstract: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, accounting for over 700,000 deaths each year. The lack of predictive and prognostic biomarkers for HCC, with effective therapy, remains a significant challenge for… read more here.

Keywords: hepatocellular carcinoma; jab1 csn5; hcc; jab1 ... See more keywords
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Jab1 Inhibition by Methanolic Extract of Moringa Oleifera Leaves in Cervical Cancer Cells: A Potent Targeted Therapeutic Approach.

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Published in 2020 at "Nutrition and cancer"

DOI: 10.1080/01635581.2020.1826989

Abstract: Modern research propounded that alteration in signaling pathways have shown strong connection with the progression of cervical cancer and modulation of these pathways by natural compounds could be a better treatment approach for the management… read more here.

Keywords: methanolic extract; extract moringa; jab1; cervical cancer ... See more keywords

Oxidized LDL-induced JAB1 influences NF-κB independent inflammatory signaling in human macrophages during foam cell formation

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Published in 2017 at "Journal of Biomedical Science"

DOI: 10.1186/s12929-017-0320-5

Abstract: BackgroundOxidized low-density lipoprotein (oxLDL) mediates the transformation of macrophages (MΦ) to cholesterol-rich foam cells and the release of pro-inflammatory cytokines during atherogenesis. JAB1 (Jun activation domain binding protein-1) is present in all stages of human… read more here.

Keywords: foam cell; jab1; cell formation; p38 ... See more keywords
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Cuproptosis related genes associated with Jab1 shapes tumor microenvironment and pharmacological profile in nasopharyngeal carcinoma

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.989286

Abstract: Background Nasopharyngeal carcinoma (NPC) is the most common subcategory of head and neck squamous cell carcinoma (HNSCC). This study focused on the roles of cuproptosis related genes and Jab1 in the tumor microenvironment of NPC… read more here.

Keywords: cell; jab1; related genes; cuproptosis related ... See more keywords
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Activation of Esterase D by FPD5 Inhibits Growth of A549 Lung Cancer Cells via JAB1/p53 Pathway

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Published in 2022 at "Genes"

DOI: 10.3390/genes13050786

Abstract: Esterase D (ESD) is widely distributed in mammals, and it plays an important role in drug metabolism, detoxification, and biomarkers and is closely related to the development of tumors. In our previous work, we found… read more here.

Keywords: jab1; growth; fpd5; p53 ... See more keywords
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Suppression of Jab1 expression inhibits proliferation and promotes apoptosis of AMC-HN-8 cells.

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Published in 2018 at "Oncology letters"

DOI: 10.3892/ol.2018.7963

Abstract: c-Jun activation domain-binding protein-1 (Jab1) is a multifunctional protein involved in cell proliferation and apoptosis, DNA damage and repair and genome stability. In a number of types of human carcinoma, the abnormal expression of Jab1… read more here.

Keywords: jab1 expression; jab1; proliferation; expression ... See more keywords