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Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00560-7
Abstract: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, accounting for over 700,000 deaths each year. The lack of predictive and prognostic biomarkers for HCC, with effective therapy, remains a significant challenge for…
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Keywords:
hepatocellular carcinoma;
jab1 csn5;
hcc;
jab1 ... See more keywords
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Published in 2020 at "Nutrition and cancer"
DOI: 10.1080/01635581.2020.1826989
Abstract: Modern research propounded that alteration in signaling pathways have shown strong connection with the progression of cervical cancer and modulation of these pathways by natural compounds could be a better treatment approach for the management…
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Keywords:
methanolic extract;
extract moringa;
jab1;
cervical cancer ... See more keywords
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Published in 2017 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-017-0320-5
Abstract: BackgroundOxidized low-density lipoprotein (oxLDL) mediates the transformation of macrophages (MΦ) to cholesterol-rich foam cells and the release of pro-inflammatory cytokines during atherogenesis. JAB1 (Jun activation domain binding protein-1) is present in all stages of human…
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Keywords:
foam cell;
jab1;
cell formation;
p38 ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.989286
Abstract: Background Nasopharyngeal carcinoma (NPC) is the most common subcategory of head and neck squamous cell carcinoma (HNSCC). This study focused on the roles of cuproptosis related genes and Jab1 in the tumor microenvironment of NPC…
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Keywords:
cell;
jab1;
related genes;
cuproptosis related ... See more keywords
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Published in 2022 at "Genes"
DOI: 10.3390/genes13050786
Abstract: Esterase D (ESD) is widely distributed in mammals, and it plays an important role in drug metabolism, detoxification, and biomarkers and is closely related to the development of tumors. In our previous work, we found…
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Keywords:
jab1;
growth;
fpd5;
p53 ... See more keywords
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Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2018.7963
Abstract: c-Jun activation domain-binding protein-1 (Jab1) is a multifunctional protein involved in cell proliferation and apoptosis, DNA damage and repair and genome stability. In a number of types of human carcinoma, the abnormal expression of Jab1…
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Keywords:
jab1 expression;
jab1;
proliferation;
expression ... See more keywords