High Throughput UHPLC-MS-Based Lipidomics Using Vacuum Jacketed Columns.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00836
Abstract: Reversed-phase UHPLC-MS is extensively employed for both the profiling of biological fluids and tissues to characterize lipid dysregulation in disease and toxicological studies. With conventional LC-MS systems the chromatographic performance and throughput are limited due… read more here.
Keywords: high throughput; vacuum jacketed; jacketed columns; compared conventional ... See more keywords
Enhanced chromatographic efficiency obtained with vacuum jacketed columns facilitates the rapid UHPLC/MS/MS-based analysis of fasiglifam in rat plasma.
Sign Up to like & getrecommendations! Published in 2022 at "Talanta"
DOI: 10.2139/ssrn.4225414
Abstract: The use of vacuum jacketed LC columns (VJC) to minimize on- and post-column band broadening to maximize chromatographic performance has been evaluated as a potential route to improved high throughput (HT) analysis. Here the use… read more here.
Keywords: rat plasma; jacketed columns; analysis; fasiglifam ... See more keywords