Articles with "jagn1" as a keyword



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JAGN1 is required for fungal killing in neutrophil extracellular traps: Implications for severe congenital neutropenia

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Published in 2018 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.4a0118-030rr

Abstract: Mutations in the gene JAGN1 were recently discovered in patients with severe congenital neutropenia (SCN). Neutrophils release neutrophil extracellular traps (NETs) consisting of decondensed chromatin decorated with various granular proteins such as neutrophil elastase and… read more here.

Keywords: neutrophil extracellular; jagn1; congenital neutropenia; jagn1 required ... See more keywords