Identification of a Novel ZBTB20-JAK2 Fusion by Mate-Pair Sequencing in a Young Adult With B-Lymphoblastic Leukemia/Lymphoma.
Sign Up to like & getrecommendations! Published in 2019 at "Mayo Clinic proceedings"
DOI: 10.1016/j.mayocp.2019.04.030
Abstract: ment in their symptoms. Other patients who had cutaneous and neurological involvement also had symptomatic improvements. The treatment was tolerated well, with only one patient discontinuing therapy because of headache. The performance status improved in… read more here.
Keywords: jak2 fusion; zbtb20 jak2; amyloidosis; identification novel ... See more keywords
Efficacy of ruxolitinib in B‐lymphoblastic leukaemia with the PCM1–JAK2 fusion gene
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17340
Abstract: The PCM1–JAK2 fusion gene resulting from a t(8;9)(p22; p24) translocation is a rare genomic abnormality reported in around 40 patients to date. This fusion gene is observed in both myeloid and lymphoid malignancies. The WHO… read more here.
Keywords: pcm1 jak2; fusion gene; jak2 fusion; jak2 ... See more keywords
Case Report: Whole genome sequencing identifies CCDC88C as a novel JAK2 fusion partner in pediatric T-cell acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.1082986
Abstract: In the present report, we applied whole genome sequencing (WGS) to genetically characterize a case of pediatric T-cell acute lymphoblastic leukemia (ALL) refractory to standard therapy. WGS identified a novel JAK2 fusion, with CCDC88C as… read more here.
Keywords: fusion; genome sequencing; pediatric cell; partner ... See more keywords