Concomitant and noncanonical JAK2 and MPL mutations in JAK2V617F‐ and MPLW515 L‐positive myelofibrosis
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DOI: 10.1002/gcc.22781
Abstract: Sequential genotyping for phenotype‐driver mutations in JAK2 (exon 14), CALR (exon 9), and MPL (exon 10) is recommended in patients with myeloproliferative neoplasms. Yet, atypical JAK2‐ and MPL‐mutations were described in some triple‐negative patients. Whether… read more here.
Keywords: mpl mutations; jak2 mpl; noncanonical jak2; mpl ... See more keywords
Calr Vs. JAK2 Vs. MPL Mutations in the Progression of Philadelphia-Negative Myeloproliferative Neoplasms
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DOI: 10.1182/blood.v130.suppl_1.5283.5283
Abstract: Objective: Myeloproliferative neoplasms (MPNs) are clonal hematopoietic disorders characterized by proliferation in one or more myeloid lineages. The classical Philadelphia (Ph) chromosome-negative MPN includes polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF). All… read more here.
Keywords: jak2 mpl; mpn; pmf patients; calr jak2 ... See more keywords