EIF4A3-induced hsa_circ_0127071 promotes human glomerular mesangial cells senescence via JAK2/STAT5 signaling pathway
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-79284-4
Abstract: Circular RNAs (circRNAs) have garnered attention for their potential involvement in the regulation of cellular aging processes. Exploring the role and mechanism of circRNAs in cellular senescence may help to identify new anti-aging therapeutic targets.… read more here.
Keywords: circ 0127071; senescence; stat5 signaling; hsa circ ... See more keywords
The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary and Comparative Oncology"
DOI: 10.1111/vco.12311
Abstract: BACKGROUND Mastocytoma are frequently diagnosed cutaneous neoplasms in dogs. In non-resectable mastocytoma patients, novel targeted drugs are often applied. The transcription factor STAT5 has been implicated in the survival of human neoplastic mast cells (MC).… read more here.
Keywords: stat5; target; canine mastocytoma; jak2 stat5 ... See more keywords
PRL/PRLR Can Promote Insulin Resistance by Activating the JAK2/STAT5 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/1456187
Abstract: Objective Although prolactin (PRL) is known to affect food intake, weight gain, and insulin resistance, its effects on lipid metabolism and underlying mechanisms remain underinvestigated. This study aimed to investigate the effects of PRL and… read more here.
Keywords: prlr; insulin resistance; stat5; group ... See more keywords
Proteomics reveals that Di Dang decoction can regulate the Jak2/Stat5 signaling pathway and inhibit apoptosis by reducing the oxidative stress response in rats with acute intracerebral hemorrhagic stroke.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.2139/ssrn.4165306
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Di Dang decoction (DDD) is a prescription used for the treatment of cerebral hemorrhage. Its use is derived from the theory of typhoid fever, it has an obvious clinical effect and it has… read more here.
Keywords: jak2 stat5; oxidative stress; stat5; expression ... See more keywords
The Dipeptide Pro-Gly Promotes IGF-1 Expression and Secretion in HepG2 and Female Mice via PepT1-JAK2/STAT5 Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2018.00424
Abstract: It has been shown that IGF-1 secretion is influenced by dietary protein or amino acid. However, whether the dipeptides elicit regulatory effects on IGF-1 secretion remains largely unclear. Thus, this study aimed to investigate the… read more here.
Keywords: secretion; igf expression; jak2 stat5; expression secretion ... See more keywords
Compound probiotics promote the growth of piglets through activating the JAK2/STAT5 signaling pathway
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2025.1480077
Abstract: Introduction Composite probiotics are characterized by their non-resistance, no residues, non-toxic effects, and pollution-free nature. To investigate their application capability in piglets, this study aims to explore the effects of composite probiotics on the growth… read more here.
Keywords: stat5 signaling; group; jak2 stat5; composite probiotics ... See more keywords