Thromboses and hemorrhages are common in MPN patients with high JAK2V617F allele burden
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DOI: 10.1007/s00277-017-3040-8
Abstract: The most common causes of morbidity and mortality in myeloproliferative neoplasms (MPN) are thrombotic and hemorrhagic complications. The JAK2V617F mutation, commonly found in MPN, correlates with several clinical and laboratory characteristics even if the relevance… read more here.
Keywords: jak2v617f allele; allele burden; mpn patients;
Association of JAK2V617F allele burden and clinical correlates in polycythemia vera: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Hematology"
DOI: 10.1007/s00277-024-05754-4
Abstract: Janus kinase 2 (JAK2) V617F mutation is present in most patients with polycythemia vera (PV). One persistently puzzling aspect unresolved is the association between JAK2V617F allele burden (also known as variant allele frequency) and the… read more here.
Keywords: jak2v617f allele; allele burden; association jak2v617f;