Engrafted JAK2V617F Clone Hijacks Resident Non-Mutated Hematopoietic System to Drive Myeloproliferative Neoplasm
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DOI: 10.1182/blood-2024-208312
Abstract: JAK2V617F is a major driver mutation in myeloproliferative neoplasms (MPN) and JAK2 inhibitors can alleviate the disease burden for patients with MPN. However, questions remain about the mechanistic role of JAK2V617F in driving the pleiotropy… read more here.
Keywords: jak2v617f; clone; hematopoietic system; jak2v617f clone ... See more keywords