Essential thrombocytemia following immune thrombocytopenia with JAK2V617F mutation
Sign Up to like & getrecommendations! Published in 2018 at "Leukemia Research Reports"
DOI: 10.1016/j.lrr.2017.12.002
Abstract: JAK2V617F mutation is found in about 60% of cases of essential thrombocytemia (ET) and represents a driving mutation. Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a low platelet (PLT) count. So far, only… read more here.
Keywords: jak2v617f; jak2v617f mutation; essential thrombocytemia; immune thrombocytopenia ... See more keywords
Prevalence of CALR mutations in splanchnic vein thrombosis: A systematic review and meta-analysis.
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DOI: 10.1016/j.thromres.2018.05.007
Abstract: BACKGROUND The prevalence of calreticulin (CALR) mutations in splanchnic vein thrombosis (SVT) varies among studies. The role of routine screening for CALR mutations in SVT patients remains a debate. AIM To synthesize the prevalence of… read more here.
Keywords: jak2v617f mutation; prevalence; calr; calr mutations ... See more keywords
JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages
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DOI: 10.3389/fimmu.2020.589048
Abstract: A substitution mutation of valine to phenylalanine at codon encoding position 617 of the Janus kinase 2 (JAK2) gene (JAK2V617F ) has been detected in myeloid cells of some individuals with higher levels of proinflammatory… read more here.
Keywords: stabilization; production; jak2v617f mutation; macrophages jak2v617f ... See more keywords