Junctional adhesion molecules mediate transendothelial migration of dendritic cell vaccine in cancer immunotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.07.029
Abstract: In vitro generated dendritic cells (DCs) have been studied in cancer immunotherapy for decades. However, the detailed molecular mechanism underlying transendothelial migration (TEM) of DC vaccine across the endothelial barrier to regional lymph nodes (LNs)… read more here.
Keywords: transendothelial migration; jaml; cancer immunotherapy; cancer ... See more keywords
Silencing of junctional adhesion molecule-like protein attenuates atherogenesis and enhances plaque stability in ApoE-/- mice.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical science"
DOI: 10.1042/cs20180561
Abstract: Background: Although junctional adhesion molecule-like protein (JAML) has recently been implicated in leukocyte recruitment during inflammation and wound repair, its role in atherosclerosis remains to be elucidated. Methods and results: First, we showed that JAML… read more here.
Keywords: junctional adhesion; molecule like; adhesion molecule; like protein ... See more keywords
JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.158571
Abstract: Although macrophages are undoubtedly attractive therapeutic targets for acute kidney injury (AKI) because of their critical roles in renal inflammation and repair, the underlying mechanisms of macrophage phenotype switching and efferocytosis in the regulation of… read more here.
Keywords: acute kidney; jaml; injury; macrophage ... See more keywords