Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma
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DOI: 10.1002/cam4.4820
Abstract: The autologous anti‐CD19 chimeric antigen receptor (CAR) T‐cell product, lisocabtagene maraleucel (liso‐cel), is administered at equal target doses of CD8+ and CD4+ CAR+ T cells. This analysis assessed safety and efficacy of liso‐cel in Japanese… read more here.
Keywords: cell; lisocabtagene maraleucel; liso cel; japanese patients ... See more keywords
Mortality of Japanese patients with Leigh syndrome: Effects of age at onset and genetic diagnosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12218
Abstract: Leigh syndrome is a major phenotype of mitochondrial diseases in children. With new therapeutic options being proposed, assessing the mortality and clinical condition of Leigh syndrome patients is crucial for evaluating therapeutics. As data are… read more here.
Keywords: leigh syndrome; onset genetic; age; genetic diagnosis ... See more keywords
Early clinical factors predicting the development of critical disease in Japanese patients with COVID‐19: A single‐center, retrospective, observational study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26599
Abstract: The factors predicting the progression of coronavirus disease‐2019 (COVID‐19) from mild to moderate to critical are unclear. We retrospectively evaluated risk factors for disease progression in Japanese patients with COVID‐19. Seventy‐four patients with laboratory‐confirmed COVID‐19… read more here.
Keywords: factors predicting; clinical factors; disease; critical disease ... See more keywords
Efficacy, safety, and pharmacokinetics of inhaled treprostinil in Japanese patients with pulmonary arterial hypertension
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DOI: 10.1002/pul2.12198
Abstract: Abstract Treprostinil is a chemically stable analog of prostacyclin, and inhaled treprostinil was developed to deliver the effects directly to the pulmonary vasculature while minimizing systemic side effects. The objective of the study was to… read more here.
Keywords: efficacy; japanese patients; inhaled treprostinil; safety pharmacokinetics ... See more keywords
Influence of multinerve‐sparing, robot‐assisted radical prostatectomy on the recovery of erection in Japanese patients
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12063
Abstract: To evaluate in Japanese patients their sexual function after robot‐assisted radical prostatectomy (RARP) and to investigate the influence of the multinerve‐sparing (NS) grade on their sexual function. read more here.
Keywords: multinerve sparing; robot assisted; japanese patients; assisted radical ... See more keywords
Thoracic and lumbar spine pedicle morphology in Japanese patients
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DOI: 10.1007/s00276-021-02707-8
Abstract: Pedicle morphology is important for intraoperative surgical anatomy and to define pedicle screw design and parameters. However, differences of pedicle size according to ethnicity and gender are not well studied. The purpose of this study… read more here.
Keywords: pedicle; anatomy; japanese patients; pedicle morphology ... See more keywords
Phase I study of ipatasertib as a single agent and in combination with abiraterone plus prednisolone in Japanese patients with advanced solid tumors
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DOI: 10.1007/s00280-019-03882-7
Abstract: Ipatasertib is a selective inhibitor of Akt, a frequently activated protein kinase in human cancers. The current study assessed the safety, tolerability, and pharmacokinetics of ipatasertib in Japanese patients with solid tumors. This was a… read more here.
Keywords: solid tumors; combination abiraterone; japanese patients; day ... See more keywords
Anti-inflammatory effect of factor-Xa inhibitors in Japanese patients with atrial fibrillation
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DOI: 10.1007/s00380-017-0962-y
Abstract: Activated factor-X (FXa) plays an important role not only in the coagulation cascade, but also in pro-inflammatory responses. However, few data exist regarding the anti-inflammatory effect of FXa inhibitors in clinical practice. The aim of… read more here.
Keywords: anti inflammatory; fxa inhibitors; inflammatory effect; inhibitors japanese ... See more keywords
Clinical outcomes for intracoronary imaging strategies at different medical facilities in Japanese patients with coronary artery disease: the SAKURA imaging PCI Registry
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DOI: 10.1007/s00380-021-01896-x
Abstract: The relationships between intracoronary imaging modalities and outcomes among Japanese patients with coronary artery disease (CAD) based on the type of medical facility providing outpatient care remain unclear. In this multicenter prospective study (SAKURA PCI… read more here.
Keywords: patients coronary; clinical outcomes; japanese patients; intracoronary imaging ... See more keywords
Intracoronary ergonovine testing among 505 consecutive Japanese patients with angina-like chest pain and unobstructed coronary artery disease
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DOI: 10.1007/s00380-021-02002-x
Abstract: Intracoronary ergonovine (ER) testing is useful for the detection of epicardial spasm (ES) and coronary microvascular spasm (CMS). We retrospectively analyzed the incidence of ES and CMS in consecutive Japanese patients with unobstructed coronary artery… read more here.
Keywords: chest pain; unobstructed coronary; japanese patients; pain ... See more keywords
ERCC1 C8092A polymorphism predicts fair survival outcome in Japanese patients with pharyngo-laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-019-05731-y
Abstract: Purpose To evaluate the prognostic significance of DNA excision repair gene polymorphisms, excision repair cross-complementation group 1 ( ERCC1 ) and X-ray repair complementing defective repair in Chinese hamster cells 1 ( XRCC1 ) polymorphisms… read more here.
Keywords: japanese patients; ercc1 c8092a; polymorphism; repair ... See more keywords