Prognostic significance of RBP2-H1 variant of JARID1B in melanoma
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DOI: 10.1186/s12885-017-3836-x
Abstract: BackgroundHistone demethylase JARID1B plays several context dependent roles in epigenetic regulation of cellular differentiation in normal development and is highly expressed in multiple human cancers. The protein is a strong transcriptional repressor capable of downregulating… read more here.
Keywords: melanoma; jarid1b; rbp2 variant; expression ... See more keywords
Histone Demethylase JARID1B Is Overexpressed in Osteosarcoma and Upregulates Cyclin D1 Expression via Demethylation of H3K27me3.
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DOI: 10.3727/096504017x14939809845080
Abstract: JARID1B has been proven to be upregulated in many human malignancies and is correlated with tumor progression. However, its expression and clinical significance in osteosarcoma are still unclear. Thus, the aim of this study was… read more here.
Keywords: histone demethylase; cyclin expression; demethylase jarid1b; h3k27me3 ... See more keywords
Jumonji AT-rich interactive domain 1B promotes the growth of pancreatic tumors via the phosphatase and tensin homolog/protein kinase B signaling pathway
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DOI: 10.3892/ol.2018.8618
Abstract: Jumonji AT-rich interactive domain 1B (JARID1B) has been revealed to remove methyl residues from methylated lysine 4 on histone H3 (H3K4) and has also been reported to be associated with the progression of numerous types… read more here.
Keywords: jumonji rich; rich interactive; interactive domain; jarid1b ... See more keywords