Development of a novel phantom for evaluating jawbone SPECT targeting medication-related osteonecrosis of the jaw
Sign Up to like & getrecommendations! Published in 2025 at "Oral Radiology"
DOI: 10.1007/s11282-025-00809-2
Abstract: We developed a new phantom for technical evaluation of jawbone single-photon emission computed tomography (SPECT) examinations for medication-related osteonecrosis of the jaw (MRONJ). In this study, we verified the utility of the phantom by determining… read more here.
Keywords: related osteonecrosis; medication related; stage lesions; phantom ... See more keywords
Design and evaluation of anisotropic octet-truss scaffolds for mimicking the mechanical behavior of human jawbone
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DOI: 10.1038/s41598-025-27136-0
Abstract: The human jawbone exhibits anisotropic mechanical behavior due to its complex trabecular microstructure, creating challenges for bioinspired scaffold design in maxillofacial implants. In this study, anisotropic scaffolds were fabricated from PolyLactic Acid (PLA) using Fused… read more here.
Keywords: mechanical behavior; human jawbone; octet truss; jawbone ... See more keywords
Identification of Periosteal Osteogenic Progenitors in Jawbone.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dental research"
DOI: 10.1177/00220345221084200
Abstract: Unlike long bones, jawbone development is mainly accomplished by intramembranous ossification resulting from the differentiation of periosteal progenitor cells. However, the spatiotemporal ontogeny of periosteal progenitor cells during jawbone development and repair remains elusive. In… read more here.
Keywords: progenitor; periosteal osteogenic; periosteal; jawbone ... See more keywords
Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-025-03745-9
Abstract: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to validate ferroptosis as a therapeutic target. We first… read more here.
Keywords: bronj; therapy; ferroptosis; jawbone ... See more keywords
Could Silent Inflammation Originating in Jawbone Cavitations Play a Role in Activating the CCL5/CCR5 Axis in Female Breast Cancer? A Diagnostic and Therapeutic Gap in Osteoimmunological Interactions
Sign Up to like & getrecommendations! Published in 2025 at "OncoTargets and Therapy"
DOI: 10.2147/ott.s526033
Abstract: Introduction Breast cancer (BC) is one of the leading causes of cancer mortality worldwide. The chemokine CCL5 and its receptor CCR5 have been demonstrated to be associated with tumour progression, immune evasion, and metastasis. Objective… read more here.
Keywords: ccr5; cancer; fdoj; ccl5 ... See more keywords
Interaction between immuno-stem dual lineages in jaw bone formation and injury repair
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2024.1359295
Abstract: The jawbone, a unique structure in the human body, undergoes faster remodeling than other bones due to the presence of stem cells and its distinct immune microenvironment. Long-term exposure of jawbones to an oral environment… read more here.
Keywords: jaw; stem; stem cells; jawbone ... See more keywords
Review of Myeloma Therapies and Their Potential for Oral and Maxillofacial Side Effects
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13174479
Abstract: Simple Summary Myeloma is a common cancer involving the bone marrow. Some of the medications used in the treatment of myeloma, including those that reduce the risk of bone fractures, can increase the chance of… read more here.
Keywords: risk; myeloma; myeloma therapies; jawbone ... See more keywords