Phenothiazine Derivatives: The Importance of Stereoisomerism in the Tolerance and Efficacy of Antimicrobials
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DOI: 10.1007/s12088-024-01309-3
Abstract: Stereoisomers are molecules that are identical in atomic constitution and bonding. The biological properties may, however, differ significantly between two enantiomers (individual stereoisomers). JBC 1847, a phenothiazine derivative with strong antimicrobial activity against Gram-positive bacteria,… read more here.
Keywords: jbc; tolerance; jbc 1847; efficacy ... See more keywords
Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration
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DOI: 10.3389/fmicb.2021.786173
Abstract: Multidrug-resistant pathogens constitute a serious global issue and, therefore, novel antimicrobials with new modes of action are urgently needed. Here, we investigated the effect of a phenothiazine derivative (JBC 1847) with high antimicrobial activity on… read more here.
Keywords: sub inhibitory; jbc 1847; insight anti; jbc ... See more keywords